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Paper Title

Nephroprotective Drugs in Unani Medicine: A Conceptual and Pharmacological Review

Authors

Dr. Shamshiya Khatoon , Dr. Darakhshan Anwar , Dr Faisal Habib , Marghoob Ahmad , ILIYAS HUSSAIN

Keywords

Unani Medicine, Nephroprotection, Muqawwiyat-e-Kulya, Chronic Kidney Disease

Abstract

The increasing prevalence of chronic kidney disease (CKD) and drug-induced nephrotoxicity has created a need for safe and effective therapeutic alternatives. Unani medicine provides a holistic approach to renal protection through the concept of Muhafiz-e-Kulya, which focuses on maintaining Mizaj (temperament), proper functioning of Quwa (faculties), and elimination of fasid maddah (morbid matter). This review aims to explore the conceptual framework of kidney function in Unani medicine and to evaluate the nephroprotective potential of Unani drugs in the light of modern scientific evidence. A comprehensive analysis of classical Unani texts along with recent pharmacological studies was carried out. The Unani system describes the kidney (Kulya) as an active organ governed by five faculties responsible for absorption, retention, transformation, discrimination, and elimination. Several drugs such as Kasni (Cichorium intybus), Gokhru (Tribulus terrestris), Biskhapra (Boerhavia diffusa), and Karafs (Apium graveolens) have shown significant nephroprotective effects through antioxidant, anti-inflammatory, and diuretic mechanisms. Compound formulations like Jawarish Zarooni Sada and Sharbat-e-Bazoori further enhance renal protection by improving detoxification and organ strength. Modern experimental studies support these traditional claims by demonstrating reduction in serum creatinine, urea levels, and renal tissue damage. The review suggests that Unani nephroprotective drugs offer a multi-targeted approach in the management of renal disorders. However, further clinical studies and standardization are required for their wider acceptance in modern medicine.

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IJCRT — journal style
"Nephroprotective Drugs in Unani Medicine: A Conceptual and Pharmacological Review", IJCRT - International Journal of Creative Research Thoughts (www.ijcrt.org), ISSN:2320-2882, Vol.14, Issue 4, page no.f46-f55, April 2026, Available :https://ijcrt.org/papers/IJCRT2604589.pdf
APA — 7th edition
Khatoon, S., Anwar, D., Habib, F., Ahmad, M., & HUSSAIN, I. (2026). Nephroprotective Drugs in Unani Medicine: A Conceptual and Pharmacological Review. International Journal of Creative Research Thoughts, 14(4), f46-f55. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2604589
MLA — 9th edition
Khatoon, Shamshiya, et al. "Nephroprotective Drugs in Unani Medicine: A Conceptual and Pharmacological Review." International Journal of Creative Research Thoughts, vol. 14, no. 4, 2026, pp. f46-f55, https://ijcrt.org/viewpaperforall.php?paper=IJCRT2604589.
Chicago — 17th, bibliography
Khatoon, Shamshiya, et al. "Nephroprotective Drugs in Unani Medicine: A Conceptual and Pharmacological Review." International Journal of Creative Research Thoughts 14, no. 4 (2026): f46-f55. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2604589.
Harvard — author–date
Khatoon, S. et al. (2026) 'Nephroprotective Drugs in Unani Medicine: A Conceptual and Pharmacological Review', International Journal of Creative Research Thoughts, 14(4), pp. f46-f55. Available at: https://ijcrt.org/viewpaperforall.php?paper=IJCRT2604589
IEEE — numbered reference
S. Khatoon, D. Anwar, F. Habib, M. Ahmad and I. HUSSAIN, "Nephroprotective Drugs in Unani Medicine: A Conceptual and Pharmacological Review," IJCRT, vol. 14, no. 4, pp. f46-f55, Apr. 2026.
Vancouver — biomedical
Khatoon S, Anwar D, Habib F, Ahmad M, HUSSAIN I. Nephroprotective Drugs in Unani Medicine: A Conceptual and Pharmacological Review. IJCRT. 2026 Apr;14(4):f46-f55.
AMA — 11th edition
Khatoon S, Anwar D, Habib F, Ahmad M, HUSSAIN I. Nephroprotective Drugs in Unani Medicine: A Conceptual and Pharmacological Review. IJCRT. 2026;14(4):f46-f55. Accessed at https://ijcrt.org/viewpaperforall.php?paper=IJCRT2604589
BibTeX — Zotero, Mendeley, LaTeX
@article{IJCRT2604589, author = {Shamshiya Khatoon and Darakhshan Anwar and Faisal Habib and Marghoob Ahmad and ILIYAS HUSSAIN}, title = {Nephroprotective Drugs in Unani Medicine: A Conceptual and Pharmacological Review}, journal = {International Journal of Creative Research Thoughts}, volume = {14}, number = {4}, pages = {f46-f55}, year = {2026}, month = {April}, issn = {2320-2882}, url = {https://ijcrt.org/viewpaperforall.php?paper=IJCRT2604589} }
RIS — EndNote, RefWorks
TY - JOUR AU - Khatoon, Shamshiya AU - Anwar, Darakhshan AU - Habib, Faisal AU - Ahmad, Marghoob AU - HUSSAIN, ILIYAS TI - Nephroprotective Drugs in Unani Medicine: A Conceptual and Pharmacological Review T2 - International Journal of Creative Research Thoughts JA - IJCRT VL - 14 IS - 4 PY - 2026 SN - 2320-2882 UR - https://ijcrt.org/viewpaperforall.php?paper=IJCRT2604589 SP - f46-f55 ER -

Issue

Volume 14 Issue 4, April-2026
Pages : f46-f55

Article Information

Pages
f46-f55
Published
April 2026
Registration ID
IJCRT_305568
Published Paper ID
IJCRT2604589
Research Area
Health Science All
Author Type
Indian Author
Location
lucknow, Uttar Pradesh, India
Licence
CC BY 4.0 · Open Access
ISSN & Impact Factor
2320-2882 · IF 9.17
Downloads
104

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International Journal of Creative Research Thoughts Published by IJCRT Publication
2320-2882 ISSN
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© 2026 — Authors hold the copyright of this article. This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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Declarations

Funding

No external funding was received for this study.

Conflict of Interest

The authors declare that they have no conflict of interest.

Acknowledgements

The authors would like to thank the reviewers and the editorial board of International Journal of Creative Research Thoughts for their careful reading and constructive comments, and all colleagues who supported the preparation of this manuscript.

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