ISSN2320-2882
Impact Factor9.17
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ESTD2013
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Paper Title
ROLE OF PRAKRITI IN DRUG RESISTANCE: AN AYURVEDIC HYPOTHESIS
Authors
Dr. Pranjal Devendra Raorane , Dr. Nayanesh D. Kambale
Keywords
Prakriti; Drug Resistance; Personalized Medicine; Agni; Pharmacogenomics; Kayachikitsa; Ayurveda
Abstract
Drug resistance has emerged as a major challenge in the management of chronic, infectious, metabolic, and inflammatory diseases in contemporary medicine. Despite appropriate diagnosis and standard therapeutic regimens, a subset of patients shows poor or diminishing response to pharmacological interventions. Ayurveda, with its individualized approach to diagnosis and treatment, offers a unique framework to understand inter-individual variability in drug response through the concept of Prakriti. Prakriti, the innate psychosomatic constitution of an individual determined at conception, governs physiological functions, metabolic capacity, disease susceptibility, and therapeutic responsiveness. This paper proposes an Ayurvedic hypothesis that drug resistance may be partially explained by Prakriti-specific variations in Agni, Dhatu Paka, Srotas, and Koshta, leading to altered drug assimilation, metabolism, distribution, and action. The article critically examines classical Ayurvedic principles, correlates them with contemporary concepts of pharmacogenomics and personalized medicine, and proposes a Prakriti-based model for understanding drug resistance. This conceptual framework opens new avenues for integrative research, individualized therapeutics, and optimized drug selection in both Ayurveda and modern medicine.
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IJCRT — journal style
"ROLE OF PRAKRITI IN DRUG RESISTANCE: AN AYURVEDIC HYPOTHESIS", IJCRT - International Journal of Creative Research Thoughts (www.ijcrt.org), ISSN:2320-2882, Vol.14, Issue 3, page no.a868-a871, March 2026, Available :https://ijcrt.org/papers/IJCRT2603106.pdf
APA — 7th edition
Raorane, P. D., & Kambale, N. D. (2026). ROLE OF PRAKRITI IN DRUG RESISTANCE: AN AYURVEDIC HYPOTHESIS. International Journal of Creative Research Thoughts, 14(3), a868-a871. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2603106
MLA — 9th edition
Raorane, Pranjal Devendra, and Nayanesh D. Kambale. "ROLE OF PRAKRITI IN DRUG RESISTANCE: AN AYURVEDIC HYPOTHESIS." International Journal of Creative Research Thoughts, vol. 14, no. 3, 2026, pp. a868-a871, https://ijcrt.org/viewpaperforall.php?paper=IJCRT2603106.
Chicago — 17th, bibliography
Raorane, Pranjal Devendra, and Nayanesh D. Kambale. "ROLE OF PRAKRITI IN DRUG RESISTANCE: AN AYURVEDIC HYPOTHESIS." International Journal of Creative Research Thoughts 14, no. 3 (2026): a868-a871. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2603106.
Harvard — author–date
Raorane, P.D. and Kambale, N.D. (2026) 'ROLE OF PRAKRITI IN DRUG RESISTANCE: AN AYURVEDIC HYPOTHESIS', International Journal of Creative Research Thoughts, 14(3), pp. a868-a871. Available at: https://ijcrt.org/viewpaperforall.php?paper=IJCRT2603106
IEEE — numbered reference
P. D. Raorane and N. D. Kambale, "ROLE OF PRAKRITI IN DRUG RESISTANCE: AN AYURVEDIC HYPOTHESIS," IJCRT, vol. 14, no. 3, pp. a868-a871, Mar. 2026.
Vancouver — biomedical
Raorane PD, Kambale ND. ROLE OF PRAKRITI IN DRUG RESISTANCE: AN AYURVEDIC HYPOTHESIS. IJCRT. 2026 Mar;14(3):a868-a871.
AMA — 11th edition
Raorane PD, Kambale ND. ROLE OF PRAKRITI IN DRUG RESISTANCE: AN AYURVEDIC HYPOTHESIS. IJCRT. 2026;14(3):a868-a871. Accessed at https://ijcrt.org/viewpaperforall.php?paper=IJCRT2603106
BibTeX — Zotero, Mendeley, LaTeX
@article{IJCRT2603106,
author = {Pranjal Devendra Raorane and Nayanesh D. Kambale},
title = {ROLE OF PRAKRITI IN DRUG RESISTANCE: AN AYURVEDIC HYPOTHESIS},
journal = {International Journal of Creative Research Thoughts},
volume = {14},
number = {3},
pages = {a868-a871},
year = {2026},
month = {March},
issn = {2320-2882},
url = {https://ijcrt.org/viewpaperforall.php?paper=IJCRT2603106}
}
RIS — EndNote, RefWorks
TY - JOUR
AU - Raorane, Pranjal Devendra
AU - Kambale, Nayanesh D.
TI - ROLE OF PRAKRITI IN DRUG RESISTANCE: AN AYURVEDIC HYPOTHESIS
T2 - International Journal of Creative Research Thoughts
JA - IJCRT
VL - 14
IS - 3
PY - 2026
SN - 2320-2882
UR - https://ijcrt.org/viewpaperforall.php?paper=IJCRT2603106
SP - a868-a871
ER -
Issue
Volume 14 Issue 3,
March-2026
Pages : a868-a871
Article Information
- Pages
- a868-a871
- Published
- March 2026
- Registration ID
- IJCRT_302518
- Published Paper ID
- IJCRT2603106
- Research Area
- Health Science All
- Author Type
- Indian Author
- Location
- Khed, Maharashtra, India
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- Request Peer Review Report
- Licence
- CC BY 4.0 · Open Access
- ISSN & Impact Factor
- 2320-2882 · IF 9.17
- Downloads
- 183
- Permanent Link
- https://ijcrt.org/viewpaperforall.php?paper=IJCRT2603106
- Published Paper PDF
- https://ijcrt.org/papers/IJCRT2603106.pdf
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