ISSN2320-2882
Impact Factor9.17
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Paper Title
IN SITU GELLING SYSTEMS FOR NASAL DRUG DELIVERY: FORMULATION STRATEGIES AND THERAPEUTIC APPLICATIONS
Authors
Trusha Patel , Mahir Ruwala , Dr. Pankaj H. Prajapati , Dr. Darshan A. Modi , Khushbu M. Patel
Keywords
Drug Delivery, In situ gel, Nasal Cavity, Nasal Delivery
Abstract
Intranasal delivery is one of the most interesting and challenging endeavors facing pharmaceutical scientists. Nasal delivery is an alternative to oral or parenteral administration due to certain limitations such as absorption of the drug, drug targeting to particular organs can cause a problem for administration through oral route. The nasal route has also been successfully used for bypassing the blood-brain barrier and afterword delivering drug molecules to the central nervous system. Also, lag time related to oral drug delivery is reduced by this route and offers noninvasiveness, self-medication, patient comfort, and patient compliance. Extend drug delivery can be attained by different new dosage forms like in situ gel. In situ formulations are drug delivery systems. In situ gel-forming systems increase the retention of drugs in the nasal cavity, and some of them also show permeation-enhancing capabilities. This article reviews the in-situ gel-forming systems used for nasal drug delivery and introduces their gelling mechanisms and other favorable features for intranasal delivery. It also describes the release patterns and drug stability of in situ gels as well as their in vivo performances and local safety following nasal administration.
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IJCRT — journal style
"IN SITU GELLING SYSTEMS FOR NASAL DRUG DELIVERY: FORMULATION STRATEGIES AND THERAPEUTIC APPLICATIONS", IJCRT - International Journal of Creative Research Thoughts (www.ijcrt.org), ISSN:2320-2882, Vol.14, Issue 2, page no.c482-c496, February 2026, Available :https://ijcrt.org/papers/IJCRT2602278.pdf
APA — 7th edition
Patel, T., Ruwala, M., Prajapati, P. H., Modi, D. A., & Patel, K. M. (2026). IN SITU GELLING SYSTEMS FOR NASAL DRUG DELIVERY: FORMULATION STRATEGIES AND THERAPEUTIC APPLICATIONS. International Journal of Creative Research Thoughts, 14(2), c482-c496. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2602278
MLA — 9th edition
Patel, Trusha, et al. "IN SITU GELLING SYSTEMS FOR NASAL DRUG DELIVERY: FORMULATION STRATEGIES AND THERAPEUTIC APPLICATIONS." International Journal of Creative Research Thoughts, vol. 14, no. 2, 2026, pp. c482-c496, https://ijcrt.org/viewpaperforall.php?paper=IJCRT2602278.
Chicago — 17th, bibliography
Patel, Trusha, et al. "IN SITU GELLING SYSTEMS FOR NASAL DRUG DELIVERY: FORMULATION STRATEGIES AND THERAPEUTIC APPLICATIONS." International Journal of Creative Research Thoughts 14, no. 2 (2026): c482-c496. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2602278.
Harvard — author–date
Patel, T. et al. (2026) 'IN SITU GELLING SYSTEMS FOR NASAL DRUG DELIVERY: FORMULATION STRATEGIES AND THERAPEUTIC APPLICATIONS', International Journal of Creative Research Thoughts, 14(2), pp. c482-c496. Available at: https://ijcrt.org/viewpaperforall.php?paper=IJCRT2602278
IEEE — numbered reference
T. Patel, M. Ruwala, P. H. Prajapati, D. A. Modi and K. M. Patel, "IN SITU GELLING SYSTEMS FOR NASAL DRUG DELIVERY: FORMULATION STRATEGIES AND THERAPEUTIC APPLICATIONS," IJCRT, vol. 14, no. 2, pp. c482-c496, Feb. 2026.
Vancouver — biomedical
Patel T, Ruwala M, Prajapati PH, Modi DA, Patel KM. IN SITU GELLING SYSTEMS FOR NASAL DRUG DELIVERY: FORMULATION STRATEGIES AND THERAPEUTIC APPLICATIONS. IJCRT. 2026 Feb;14(2):c482-c496.
AMA — 11th edition
Patel T, Ruwala M, Prajapati PH, Modi DA, Patel KM. IN SITU GELLING SYSTEMS FOR NASAL DRUG DELIVERY: FORMULATION STRATEGIES AND THERAPEUTIC APPLICATIONS. IJCRT. 2026;14(2):c482-c496. Accessed at https://ijcrt.org/viewpaperforall.php?paper=IJCRT2602278
BibTeX — Zotero, Mendeley, LaTeX
@article{IJCRT2602278,
author = {Trusha Patel and Mahir Ruwala and Pankaj H. Prajapati and Darshan A. Modi and Khushbu M. Patel},
title = {IN SITU GELLING SYSTEMS FOR NASAL DRUG DELIVERY: FORMULATION STRATEGIES AND THERAPEUTIC APPLICATIONS},
journal = {International Journal of Creative Research Thoughts},
volume = {14},
number = {2},
pages = {c482-c496},
year = {2026},
month = {February},
issn = {2320-2882},
url = {https://ijcrt.org/viewpaperforall.php?paper=IJCRT2602278}
}
RIS — EndNote, RefWorks
TY - JOUR
AU - Patel, Trusha
AU - Ruwala, Mahir
AU - Prajapati, Pankaj H.
AU - Modi, Darshan A.
AU - Patel, Khushbu M.
TI - IN SITU GELLING SYSTEMS FOR NASAL DRUG DELIVERY: FORMULATION STRATEGIES AND THERAPEUTIC APPLICATIONS
T2 - International Journal of Creative Research Thoughts
JA - IJCRT
VL - 14
IS - 2
PY - 2026
SN - 2320-2882
UR - https://ijcrt.org/viewpaperforall.php?paper=IJCRT2602278
SP - c482-c496
ER -
Issue
Volume 14 Issue 2,
February-2026
Pages : c482-c496
Article Information
- Published In
- International Journal of Creative Research Thoughts — Volume 14, Issue 2, February 2026
- Pages
- c482-c496
- Published
- February 2026
- Registration ID
- IJCRT_301471
- Published Paper ID
- IJCRT2602278
- Research Area
- Pharmacy All
- Author Type
- Indian Author
- Location
- Mehsana, Gujarat, India
- Peer Review
- Request Peer Review Report
- Licence
- CC BY 4.0 · Open Access
- ISSN & Impact Factor
- 2320-2882 · IF 9.17
- Downloads
- 176
- Permanent Link
- https://ijcrt.org/viewpaperforall.php?paper=IJCRT2602278
- Published Paper PDF
- https://ijcrt.org/papers/IJCRT2602278.pdf
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