ISSN2320-2882
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Paper Title
Efficacy of Ondansetron Alone versus Ondansetron Combined with Dexamethasone in Preventing Postoperative Nausea and Vomiting under General Anesthesia
Authors
AFREEN JAVEED , DR. VIVEK GUPTA , DR. ABHISHEK GUPTA , RIZWAN MUNEER
Keywords
Keywords: PONV, Ondansetron, Dexamethasone
Abstract
Introduction: Post-operative nausea and vomiting (PONV) is a common and distressing complication in the post-operative period. It increases patient discomfort, prolongs post-anaesthesia care unit (PACU) stay, raises the risk of postoperative complications and readmission, and adds to healthcare costs. Ondansetron and dexamethasone are widely used for PONV prophylaxis.
Methods: This prospective study included 60 patients aged 20-65 years, weighing 55-70 kg, with ASA physical status I or II, scheduled for elective abdominal surgery under general anesthesia. Patients were randomly divided into two groups (n=30 each). Group I received ondansetron 4 mg IV, while Group II received ondansetron 4 mg IV plus dexamethasone 4 mg IV. Study drugs were administered intravenously 15 minutes before induction of anesthesia.
Results: In Group II, no patient experienced PONV during the first two postoperative hours, and only one patient reported nausea and vomiting by the end of postoperative day 0. In contrast, Group I had four patients with PONV within the first two hours and ten patients by the end of postoperative day 0.
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IJCRT — journal style
"Efficacy of Ondansetron Alone versus Ondansetron Combined with Dexamethasone in Preventing Postoperative Nausea and Vomiting under General Anesthesia", IJCRT - International Journal of Creative Research Thoughts (www.ijcrt.org), ISSN:2320-2882, Vol.14, Issue 1, page no.c929-c942, January 2026, Available :https://ijcrt.org/papers/IJCRT2601357.pdf
APA — 7th edition
JAVEED, A., GUPTA, V., GUPTA, A., & MUNEER, R. (2026). Efficacy of Ondansetron Alone versus Ondansetron Combined with Dexamethasone in Preventing Postoperative Nausea and Vomiting under General Anesthesia. International Journal of Creative Research Thoughts, 14(1), c929-c942. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2601357
MLA — 9th edition
JAVEED, AFREEN, et al. "Efficacy of Ondansetron Alone versus Ondansetron Combined with Dexamethasone in Preventing Postoperative Nausea and Vomiting under General Anesthesia." International Journal of Creative Research Thoughts, vol. 14, no. 1, 2026, pp. c929-c942, https://ijcrt.org/viewpaperforall.php?paper=IJCRT2601357.
Chicago — 17th, bibliography
JAVEED, AFREEN, et al. "Efficacy of Ondansetron Alone versus Ondansetron Combined with Dexamethasone in Preventing Postoperative Nausea and Vomiting under General Anesthesia." International Journal of Creative Research Thoughts 14, no. 1 (2026): c929-c942. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2601357.
Harvard — author–date
JAVEED, A. et al. (2026) 'Efficacy of Ondansetron Alone versus Ondansetron Combined with Dexamethasone in Preventing Postoperative Nausea and Vomiting under General Anesthesia', International Journal of Creative Research Thoughts, 14(1), pp. c929-c942. Available at: https://ijcrt.org/viewpaperforall.php?paper=IJCRT2601357
IEEE — numbered reference
A. JAVEED, V. GUPTA, A. GUPTA and R. MUNEER, "Efficacy of Ondansetron Alone versus Ondansetron Combined with Dexamethasone in Preventing Postoperative Nausea and Vomiting under General Anesthesia," IJCRT, vol. 14, no. 1, pp. c929-c942, Jan. 2026.
Vancouver — biomedical
JAVEED A, GUPTA V, GUPTA A, MUNEER R. Efficacy of Ondansetron Alone versus Ondansetron Combined with Dexamethasone in Preventing Postoperative Nausea and Vomiting under General Anesthesia. IJCRT. 2026 Jan;14(1):c929-c942.
AMA — 11th edition
JAVEED A, GUPTA V, GUPTA A, MUNEER R. Efficacy of Ondansetron Alone versus Ondansetron Combined with Dexamethasone in Preventing Postoperative Nausea and Vomiting under General Anesthesia. IJCRT. 2026;14(1):c929-c942. Accessed at https://ijcrt.org/viewpaperforall.php?paper=IJCRT2601357
BibTeX — Zotero, Mendeley, LaTeX
@article{IJCRT2601357,
author = {AFREEN JAVEED and VIVEK GUPTA and ABHISHEK GUPTA and RIZWAN MUNEER},
title = {Efficacy of Ondansetron Alone versus Ondansetron Combined with Dexamethasone in Preventing Postoperative Nausea and Vomiting under General Anesthesia},
journal = {International Journal of Creative Research Thoughts},
volume = {14},
number = {1},
pages = {c929-c942},
year = {2026},
month = {January},
issn = {2320-2882},
url = {https://ijcrt.org/viewpaperforall.php?paper=IJCRT2601357}
}
RIS — EndNote, RefWorks
TY - JOUR
AU - JAVEED, AFREEN
AU - GUPTA, VIVEK
AU - GUPTA, ABHISHEK
AU - MUNEER, RIZWAN
TI - Efficacy of Ondansetron Alone versus Ondansetron Combined with Dexamethasone in Preventing Postoperative Nausea and Vomiting under General Anesthesia
T2 - International Journal of Creative Research Thoughts
JA - IJCRT
VL - 14
IS - 1
PY - 2026
SN - 2320-2882
UR - https://ijcrt.org/viewpaperforall.php?paper=IJCRT2601357
SP - c929-c942
ER -
Issue
Volume 14 Issue 1,
January-2026
Pages : c929-c942
Article Information
- Pages
- c929-c942
- Published
- January 2026
- Registration ID
- IJCRT_300389
- Published Paper ID
- IJCRT2601357
- Research Area
- Humanities All
- Author Type
- Indian Author
- Location
- KHARAR, J&K, India
- Peer Review
- Request Peer Review Report
- Licence
- CC BY 4.0 · Open Access
- ISSN & Impact Factor
- 2320-2882 · IF 9.17
- Downloads
- 160
- Permanent Link
- https://ijcrt.org/viewpaperforall.php?paper=IJCRT2601357
- Published Paper PDF
- https://ijcrt.org/papers/IJCRT2601357.pdf
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