ISSN2320-2882
Impact Factor9.17
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ESTD2013
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AccessOpen
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Paper Title
Bubble Liposomes and Ultrasound-Triggered Drug Release: Novel Paradigms in Nanomedicines
Authors
Girwalkar Gaurav G , Dr Vishweshwar Dharashive , Kapse Vidya , Hengne Sakshi
Keywords
Ultrasound-responsive drug delivery, Non-invasive therapy, Spatially controlled release, Liposomes, Phospholipid bilayers, Biocompatibility, Drug encapsulation etc.
Abstract
Ultrasound-responsive nanocarriers have emerged as a transformative approach for targeted and controlled drug delivery, offering spatiotemporal precision unattainable with conventional systems. Among these, bubble liposomes (BLs) lipid vesicles encapsulating gas or perfluorocarbon cores combine the biocompatibility of liposomes with the echogenicity of microbubbles, enabling both diagnostic imaging and therapeutic delivery. Exposure to ultrasound triggers bubble oscillation and cavitation, resulting in transient perturbation of the liposomal membrane and controlled release of encapsulated drugs, nucleic acids, or imaging agents at the target site. This theranostic functionality reduces systemic toxicity and enhances therapeutic efficacy.
This review provides a comprehensive discussion on the structural features, classification, preparation methods, physicochemical factors, mechanisms of action, evaluation strategies, and applications of bubble liposomes. Additionally, the review examines current limitations and future opportunities in translating this technology to clinical use. By integrating imaging and therapy, BLs represent a novel paradigm in nanomedicine, bridging diagnostic and therapeutic modalities.
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IJCRT — journal style
"Bubble Liposomes and Ultrasound-Triggered Drug Release: Novel Paradigms in Nanomedicines", IJCRT - International Journal of Creative Research Thoughts (www.ijcrt.org), ISSN:2320-2882, Vol.13, Issue 11, page no.j589-j600, November 2025, Available :https://ijcrt.org/papers/IJCRT25A1238.pdf
APA — 7th edition
G, G. G., Dharashive, V., Vidya, K., & Sakshi, H. (2025). Bubble Liposomes and Ultrasound-Triggered Drug Release: Novel Paradigms in Nanomedicines. International Journal of Creative Research Thoughts, 13(11), j589-j600. https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1238
MLA — 9th edition
G, Girwalkar Gaurav, et al. "Bubble Liposomes and Ultrasound-Triggered Drug Release: Novel Paradigms in Nanomedicines." International Journal of Creative Research Thoughts, vol. 13, no. 11, 2025, pp. j589-j600, https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1238.
Chicago — 17th, bibliography
G, Girwalkar Gaurav, et al. "Bubble Liposomes and Ultrasound-Triggered Drug Release: Novel Paradigms in Nanomedicines." International Journal of Creative Research Thoughts 13, no. 11 (2025): j589-j600. https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1238.
Harvard — author–date
G, G.G. et al. (2025) 'Bubble Liposomes and Ultrasound-Triggered Drug Release: Novel Paradigms in Nanomedicines', International Journal of Creative Research Thoughts, 13(11), pp. j589-j600. Available at: https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1238
IEEE — numbered reference
G. G. G, V. Dharashive, K. Vidya and H. Sakshi, "Bubble Liposomes and Ultrasound-Triggered Drug Release: Novel Paradigms in Nanomedicines," IJCRT, vol. 13, no. 11, pp. j589-j600, Nov. 2025.
Vancouver — biomedical
G GG, Dharashive V, Vidya K, Sakshi H. Bubble Liposomes and Ultrasound-Triggered Drug Release: Novel Paradigms in Nanomedicines. IJCRT. 2025 Nov;13(11):j589-j600.
AMA — 11th edition
G GG, Dharashive V, Vidya K, Sakshi H. Bubble Liposomes and Ultrasound-Triggered Drug Release: Novel Paradigms in Nanomedicines. IJCRT. 2025;13(11):j589-j600. Accessed at https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1238
BibTeX — Zotero, Mendeley, LaTeX
@article{IJCRT25A1238,
author = {Girwalkar Gaurav G and Vishweshwar Dharashive and Kapse Vidya and Hengne Sakshi},
title = {Bubble Liposomes and Ultrasound-Triggered Drug Release: Novel Paradigms in Nanomedicines},
journal = {International Journal of Creative Research Thoughts},
volume = {13},
number = {11},
pages = {j589-j600},
year = {2025},
month = {November},
issn = {2320-2882},
url = {https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1238}
}
RIS — EndNote, RefWorks
TY - JOUR
AU - G, Girwalkar Gaurav
AU - Dharashive, Vishweshwar
AU - Vidya, Kapse
AU - Sakshi, Hengne
TI - Bubble Liposomes and Ultrasound-Triggered Drug Release: Novel Paradigms in Nanomedicines
T2 - International Journal of Creative Research Thoughts
JA - IJCRT
VL - 13
IS - 11
PY - 2025
SN - 2320-2882
UR - https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1238
SP - j589-j600
ER -
Issue
Volume 13 Issue 11,
November-2025
Pages : j589-j600
Article Information
- Published In
- International Journal of Creative Research Thoughts — Volume 13, Issue 11, November 2025
- Pages
- j589-j600
- Published
- November 2025
- Registration ID
- IJCRT_297893
- Published Paper ID
- IJCRT25A1238
- Research Area
- Pharmacy All
- Author Type
- Indian Author
- Location
- Latur, Maharashtra, India
- Peer Review
- Request Peer Review Report
- Licence
- CC BY 4.0 · Open Access
- ISSN & Impact Factor
- 2320-2882 · IF 9.17
- Downloads
- 305
- Permanent Link
- https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1238
- Published Paper PDF
- https://ijcrt.org/papers/IJCRT25A1238.pdf
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