ISSN2320-2882
Impact Factor9.17
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Paper Title
Fungal Infections: Pathophysiology, Allopathic Treatment and Herbal Alternatives - A Comprehensive Integrative Review
Authors
Anand M Mhaske , Mr. Ashish Umale , Dr. Swati Deshmukh
Keywords
Fungal Infections, Antifungal Agents, Herbal Medicine, Calotropis gigantea, Aloe vera, Curcuma longa, Phytochemicals, Antifungal Resistance, Medicinal Plants, Natural Therapy.
Abstract
Fungal infections have become a major global health issue, especially for people with weakened immune systems. These infections can range from mild, surface-level conditions to severe, life-threatening diseases caused by fungi like Candida, Aspergillus, and Cryptococcus. Several factors make someone more prone to these infections, including conditions such as diabetes, HIV/AIDS, obesity, the long-term use of antibiotics, and being in a hospital setting. While drugs like azoles, polyenes, and echinocandins are effective against fungal infections, using them for long periods can lead to problems like toxicity, resistance to the drugs, and high costs. To address these issues, there is growing interest in using herbal medicines as a safer and more sustainable alternative. Plants such as Calotropis gigantea, Aloe vera, and Curcuma longa contain active compounds like flavonoids, saponins, and alkaloids that can damage the structure of fungal cells, stop the production of ergosterol (which is important for fungi), and create oxidative stress within the fungal cells. These natural compounds not only show strong antifungal effects but also help support the immune system and lower inflammation. Combining herbal treatments with traditional antifungal medications could be a promising way to better manage and prevent fungal infections with fewer side effects and lower chances of drug resistance. However, more research and clinical testing are needed to create reliable, effective, and safe herbal-based treatments for fungal infections.
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IJCRT — journal style
"Fungal Infections: Pathophysiology, Allopathic Treatment and Herbal Alternatives - A Comprehensive Integrative Review", IJCRT - International Journal of Creative Research Thoughts (www.ijcrt.org), ISSN:2320-2882, Vol.13, Issue 11, page no.j430-j442, November 2025, Available :https://ijcrt.org/papers/IJCRT25A1215.pdf
APA — 7th edition
Mhaske, A. M., Umale, A., & Deshmukh, S. (2025). Fungal Infections: Pathophysiology, Allopathic Treatment and Herbal Alternatives - A Comprehensive Integrative Review. International Journal of Creative Research Thoughts, 13(11), j430-j442. https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1215
MLA — 9th edition
Mhaske, Anand M, et al. "Fungal Infections: Pathophysiology, Allopathic Treatment and Herbal Alternatives - A Comprehensive Integrative Review." International Journal of Creative Research Thoughts, vol. 13, no. 11, 2025, pp. j430-j442, https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1215.
Chicago — 17th, bibliography
Mhaske, Anand M, Ashish Umale, and Swati Deshmukh. "Fungal Infections: Pathophysiology, Allopathic Treatment and Herbal Alternatives - A Comprehensive Integrative Review." International Journal of Creative Research Thoughts 13, no. 11 (2025): j430-j442. https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1215.
Harvard — author–date
Mhaske, A.M., Umale, A. and Deshmukh, S. (2025) 'Fungal Infections: Pathophysiology, Allopathic Treatment and Herbal Alternatives - A Comprehensive Integrative Review', International Journal of Creative Research Thoughts, 13(11), pp. j430-j442. Available at: https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1215
IEEE — numbered reference
A. M. Mhaske, A. Umale and S. Deshmukh, "Fungal Infections: Pathophysiology, Allopathic Treatment and Herbal Alternatives - A Comprehensive Integrative Review," IJCRT, vol. 13, no. 11, pp. j430-j442, Nov. 2025.
Vancouver — biomedical
Mhaske AM, Umale A, Deshmukh S. Fungal Infections: Pathophysiology, Allopathic Treatment and Herbal Alternatives - A Comprehensive Integrative Review. IJCRT. 2025 Nov;13(11):j430-j442.
AMA — 11th edition
Mhaske AM, Umale A, Deshmukh S. Fungal Infections: Pathophysiology, Allopathic Treatment and Herbal Alternatives - A Comprehensive Integrative Review. IJCRT. 2025;13(11):j430-j442. Accessed at https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1215
BibTeX — Zotero, Mendeley, LaTeX
@article{IJCRT25A1215,
author = {Anand M Mhaske and Ashish Umale and Swati Deshmukh},
title = {Fungal Infections: Pathophysiology, Allopathic Treatment and Herbal Alternatives - A Comprehensive Integrative Review},
journal = {International Journal of Creative Research Thoughts},
volume = {13},
number = {11},
pages = {j430-j442},
year = {2025},
month = {November},
issn = {2320-2882},
url = {https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1215}
}
RIS — EndNote, RefWorks
TY - JOUR
AU - Mhaske, Anand M
AU - Umale, Ashish
AU - Deshmukh, Swati
TI - Fungal Infections: Pathophysiology, Allopathic Treatment and Herbal Alternatives - A Comprehensive Integrative Review
T2 - International Journal of Creative Research Thoughts
JA - IJCRT
VL - 13
IS - 11
PY - 2025
SN - 2320-2882
UR - https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1215
SP - j430-j442
ER -
Issue
Volume 13 Issue 11,
November-2025
Pages : j430-j442
Article Information
- Published In
- International Journal of Creative Research Thoughts — Volume 13, Issue 11, November 2025
- Pages
- j430-j442
- Published
- November 2025
- Registration ID
- IJCRT_297401
- Published Paper ID
- IJCRT25A1215
- Research Area
- Science and Technology
- Author Type
- Indian Author
- Location
- India
- Peer Review
- Request Peer Review Report
- Licence
- CC BY 4.0 · Open Access
- ISSN & Impact Factor
- 2320-2882 · IF 9.17
- Downloads
- 236
- Permanent Link
- https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1215
- Published Paper PDF
- https://ijcrt.org/papers/IJCRT25A1215.pdf
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