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Paper Title

Polymeric Micelles for Topical Anti-inflammatory Drug Delivery: Advances and Future Perspectives

Authors

Mali Pooja D , Dr.Fugate Ajay R , Pawar Vitthal D , Narayankar Pramod S , Hajare Vinod T

Keywords

Polymeric micelles, Topical gel, Anti-inflammatory drug; controlled release, Nanocarrier; skin penetration; sustained delivery.

Abstract

Topical drug delivery has gained significant attention in recent years due to its ability to provide localized therapeutic effects while minimizing systemic side effects. Among various topical formulations, polymeric micelle-based gels have emerged as a promising platform for the delivery of anti-inflammatory drugs. Polymeric micelles are nanosized colloidal carriers formed by the self-assembly of amphiphilic block copolymers in aqueous solutions, offering enhanced solubility, stability, and controlled release of poorly water-soluble drugs. The incorporation of anti-inflammatory drugs into polymeric micelles improves their permeation through the stratum corneum, resulting in increased bioavailability at the site of inflammation. Additionally, polymeric micelle gels provide sustained drug release, reduce dosing frequency, and improve patient compliance. This literature review focuses on the formulation strategies, evaluation parameters, advantages, limitations, and potential applications of polymeric micelle-based topical gels for anti-inflammatory therapy. It also discusses critical factors influencing micelle formation, drug encapsulation efficiency, and release kinetics. Furthermore, the review highlights emerging opportunities, ongoing challenges, and future perspectives in the development of polymeric micelle-based topical drug delivery system. Understanding these aspects is essential for designing effective, safe, and patient-friendly topical formulations that can offer targeted therapy with minimal systematic exposure.

How To Cite

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IJCRT — journal style
"Polymeric Micelles for Topical Anti-inflammatory Drug Delivery: Advances and Future Perspectives", IJCRT - International Journal of Creative Research Thoughts (www.ijcrt.org), ISSN:2320-2882, Vol.13, Issue 11, page no.i482-i498, November 2025, Available :https://ijcrt.org/papers/IJCRT25A1109.pdf
APA — 7th edition
D, M. P., R, D. F. A., D, P. V., S, N. P., & T, H. V. (2025). Polymeric Micelles for Topical Anti-inflammatory Drug Delivery: Advances and Future Perspectives. International Journal of Creative Research Thoughts, 13(11), i482-i498. https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1109
MLA — 9th edition
D, Mali Pooja, et al. "Polymeric Micelles for Topical Anti-inflammatory Drug Delivery: Advances and Future Perspectives." International Journal of Creative Research Thoughts, vol. 13, no. 11, 2025, pp. i482-i498, https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1109.
Chicago — 17th, bibliography
D, Mali Pooja, et al. "Polymeric Micelles for Topical Anti-inflammatory Drug Delivery: Advances and Future Perspectives." International Journal of Creative Research Thoughts 13, no. 11 (2025): i482-i498. https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1109.
Harvard — author–date
D, M.P. et al. (2025) 'Polymeric Micelles for Topical Anti-inflammatory Drug Delivery: Advances and Future Perspectives', International Journal of Creative Research Thoughts, 13(11), pp. i482-i498. Available at: https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1109
IEEE — numbered reference
M. P. D, D. F. A. R, P. V. D, N. P. S and H. V. T, "Polymeric Micelles for Topical Anti-inflammatory Drug Delivery: Advances and Future Perspectives," IJCRT, vol. 13, no. 11, pp. i482-i498, Nov. 2025.
Vancouver — biomedical
D MP, R DFA, D PV, S NP, T HV. Polymeric Micelles for Topical Anti-inflammatory Drug Delivery: Advances and Future Perspectives. IJCRT. 2025 Nov;13(11):i482-i498.
AMA — 11th edition
D MP, R DFA, D PV, S NP, T HV. Polymeric Micelles for Topical Anti-inflammatory Drug Delivery: Advances and Future Perspectives. IJCRT. 2025;13(11):i482-i498. Accessed at https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1109
BibTeX — Zotero, Mendeley, LaTeX
@article{IJCRT25A1109, author = {Mali Pooja D and Dr.Fugate Ajay R and Pawar Vitthal D and Narayankar Pramod S and Hajare Vinod T}, title = {Polymeric Micelles for Topical Anti-inflammatory Drug Delivery: Advances and Future Perspectives}, journal = {International Journal of Creative Research Thoughts}, volume = {13}, number = {11}, pages = {i482-i498}, year = {2025}, month = {November}, issn = {2320-2882}, url = {https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1109} }
RIS — EndNote, RefWorks
TY - JOUR AU - D, Mali Pooja AU - R, Dr.Fugate Ajay AU - D, Pawar Vitthal AU - S, Narayankar Pramod AU - T, Hajare Vinod TI - Polymeric Micelles for Topical Anti-inflammatory Drug Delivery: Advances and Future Perspectives T2 - International Journal of Creative Research Thoughts JA - IJCRT VL - 13 IS - 11 PY - 2025 SN - 2320-2882 UR - https://ijcrt.org/viewpaperforall.php?paper=IJCRT25A1109 SP - i482-i498 ER -

Issue

Volume 13 Issue 11, November-2025
Pages : i482-i498

Article Information

Pages
i482-i498
Published
November 2025
Registration ID
IJCRT_297553
Published Paper ID
IJCRT25A1109
Research Area
Pharmacy All
Author Type
Indian Author
Location
Latur, Maharashtra, India
Licence
CC BY 4.0 · Open Access
ISSN & Impact Factor
2320-2882 · IF 9.17
Downloads
169

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International Journal of Creative Research Thoughts Published by IJCRT Publication
2320-2882 ISSN
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© 2025 — Authors hold the copyright of this article. This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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Declarations

Funding

No external funding was received for this study.

Conflict of Interest

The authors declare that they have no conflict of interest.

Acknowledgements

The authors would like to thank the reviewers and the editorial board of International Journal of Creative Research Thoughts for their careful reading and constructive comments, and all colleagues who supported the preparation of this manuscript.

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