ISSN2320-2882
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Paper Title

Self nanoemulsifyng Drug Delivery system (SNEDDS) optimization strategies, mechanism and Applications in Oral Drug Delivery

Authors

Ghorpade Gajanan Ramdas , Mohammad Zishan Ibrahim , Dr. Jameel Ahmed

Keywords

Self nanoemulsifying drug delivery system (SNEDDS)

Abstract

Oral drug delivery remains the most preferred route for drug administration due to its convenience, cost-effectiveness, and high patient compliance. However, a major challenge in oral drug delivery is the poor aqueous solubility and limited bioavailability of many newly developed drugs. Nearly 40-60% of new chemical entities (NCEs) belong to Biopharmaceutical Classification System (BCS) Class II and IV, characterized by low solubility and/or permeability. Poor solubility leads to erratic absorption, delayed onset of action, and variable therapeutic outcomes. Conventional oral formulations such as tablets and capsules often fail to achieve adequate systemic exposure for lipophilic drugs, as dissolution in the gastrointestinal (GI) fluids becomes the rate-limiting step. In response to these challenges, lipid-based formulations (LBFs) have emerged as promising alternatives, offering improved solubilization and lymphatic transport.

How To Cite

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IJCRT — journal style
"Self nanoemulsifyng Drug Delivery system (SNEDDS) optimization strategies, mechanism and Applications in Oral Drug Delivery", IJCRT - International Journal of Creative Research Thoughts (www.ijcrt.org), ISSN:2320-2882, Vol.13, Issue 12, page no.d21-d38, December 2025, Available :https://ijcrt.org/papers/IJCRT2512355.pdf
APA — 7th edition
Ramdas, G. G., Ibrahim, M. Z., & Ahmed, J. (2025). Self nanoemulsifyng Drug Delivery system (SNEDDS) optimization strategies, mechanism and Applications in Oral Drug Delivery. International Journal of Creative Research Thoughts, 13(12), d21-d38. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2512355
MLA — 9th edition
Ramdas, Ghorpade Gajanan, et al. "Self nanoemulsifyng Drug Delivery system (SNEDDS) optimization strategies, mechanism and Applications in Oral Drug Delivery." International Journal of Creative Research Thoughts, vol. 13, no. 12, 2025, pp. d21-d38, https://ijcrt.org/viewpaperforall.php?paper=IJCRT2512355.
Chicago — 17th, bibliography
Ramdas, Ghorpade Gajanan, Mohammad Zishan Ibrahim, and Jameel Ahmed. "Self nanoemulsifyng Drug Delivery system (SNEDDS) optimization strategies, mechanism and Applications in Oral Drug Delivery." International Journal of Creative Research Thoughts 13, no. 12 (2025): d21-d38. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2512355.
Harvard — author–date
Ramdas, G.G., Ibrahim, M.Z. and Ahmed, J. (2025) 'Self nanoemulsifyng Drug Delivery system (SNEDDS) optimization strategies, mechanism and Applications in Oral Drug Delivery', International Journal of Creative Research Thoughts, 13(12), pp. d21-d38. Available at: https://ijcrt.org/viewpaperforall.php?paper=IJCRT2512355
IEEE — numbered reference
G. G. Ramdas, M. Z. Ibrahim and J. Ahmed, "Self nanoemulsifyng Drug Delivery system (SNEDDS) optimization strategies, mechanism and Applications in Oral Drug Delivery," IJCRT, vol. 13, no. 12, pp. d21-d38, Dec. 2025.
Vancouver — biomedical
Ramdas GG, Ibrahim MZ, Ahmed J. Self nanoemulsifyng Drug Delivery system (SNEDDS) optimization strategies, mechanism and Applications in Oral Drug Delivery. IJCRT. 2025 Dec;13(12):d21-d38.
AMA — 11th edition
Ramdas GG, Ibrahim MZ, Ahmed J. Self nanoemulsifyng Drug Delivery system (SNEDDS) optimization strategies, mechanism and Applications in Oral Drug Delivery. IJCRT. 2025;13(12):d21-d38. Accessed at https://ijcrt.org/viewpaperforall.php?paper=IJCRT2512355
BibTeX — Zotero, Mendeley, LaTeX
@article{IJCRT2512355, author = {Ghorpade Gajanan Ramdas and Mohammad Zishan Ibrahim and Jameel Ahmed}, title = {Self nanoemulsifyng Drug Delivery system (SNEDDS) optimization strategies, mechanism and Applications in Oral Drug Delivery}, journal = {International Journal of Creative Research Thoughts}, volume = {13}, number = {12}, pages = {d21-d38}, year = {2025}, month = {December}, issn = {2320-2882}, url = {https://ijcrt.org/viewpaperforall.php?paper=IJCRT2512355} }
RIS — EndNote, RefWorks
TY - JOUR AU - Ramdas, Ghorpade Gajanan AU - Ibrahim, Mohammad Zishan AU - Ahmed, Jameel TI - Self nanoemulsifyng Drug Delivery system (SNEDDS) optimization strategies, mechanism and Applications in Oral Drug Delivery T2 - International Journal of Creative Research Thoughts JA - IJCRT VL - 13 IS - 12 PY - 2025 SN - 2320-2882 UR - https://ijcrt.org/viewpaperforall.php?paper=IJCRT2512355 SP - d21-d38 ER -

Issue

Volume 13 Issue 12, December-2025
Pages : d21-d38

Article Information

Pages
d21-d38
Published
December 2025
Registration ID
IJCRT_298484
Published Paper ID
IJCRT2512355
Research Area
Pharmacy All
Author Type
Indian Author
Location
Palam, Maharashtra, India
Licence
CC BY 4.0 · Open Access
ISSN & Impact Factor
2320-2882 · IF 9.17
Downloads
230

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International Journal of Creative Research Thoughts Published by IJCRT Publication
2320-2882 ISSN
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© 2025 — Authors hold the copyright of this article. This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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Declarations

Funding

No external funding was received for this study.

Conflict of Interest

The authors declare that they have no conflict of interest.

Acknowledgements

The authors would like to thank the reviewers and the editorial board of International Journal of Creative Research Thoughts for their careful reading and constructive comments, and all colleagues who supported the preparation of this manuscript.

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