ISSN2320-2882
Impact Factor9.17
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CrossRefDOI
ESTD2013
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Paper Title
Chromatographic Techniques & Role of lon Exchange.
Authors
Ashish Vinod Ghanbahadur , Snehal Trimbak Daud , Dr. D. K. Vir , Payal Ashok Waykos , Vaibhav Haridas Vaidya
Keywords
Ion-Exchange Chromatography (IEC), Charged Biomolecule Separation, Stationary Phase Functional Groups, Protein Purification, Biopharmaceutical Analysis, Chromatographic Techniques, Anion and Cation Exchanger
Abstract
Ion-exchange chromatography (IEC) is one of the most versatile and widely used chromatographic techniques for the separation, purification, and quantitative analysis of charged biomolecules. This review highlights the fundamental principles, operational mechanisms, and diverse applications of IEC in pharmaceutical, biochemical, environmental, and industrial research. Ion-exchange resins containing functional cationic or anionic groups interact with oppositely charged analytes, allowing highly selective and efficient separation based on charge density, ionic strength, pKa, and molecular structure. Advancements in stationary phase chemistry, membrane-based ion exchangers, monolithic columns, and coupled techniques such as ion-exchange chromatography-mass spectrometry (IEC-MS) have significantly improved resolution, speed, and sensitivity. IEC has become indispensable for purification of therapeutic proteins, plasmid DNA, monoclonal antibodies, peptides, and complex biological mixtures, as well as for water quality and environmental monitoring. Recent developments in high-performance ion-exchange materials, mixed-mode exchangers, and continuous chromatography have expanded its role in bioprocessing and analytical science. This review compiles updated research findings, technological progress, and future prospects of IEC.
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IJCRT — journal style
"Chromatographic Techniques & Role of lon Exchange.", IJCRT - International Journal of Creative Research Thoughts (www.ijcrt.org), ISSN:2320-2882, Vol.13, Issue 11, page no.i208-i213, November 2025, Available :https://ijcrt.org/papers/IJCRT2511971.pdf
APA — 7th edition
Ghanbahadur, A. V., Daud, S. T., Vir, D. K., Waykos, P. A., & Vaidya, V. H. (2025). Chromatographic Techniques & Role of lon Exchange. International Journal of Creative Research Thoughts, 13(11), i208-i213. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511971
MLA — 9th edition
Ghanbahadur, Ashish Vinod, et al. "Chromatographic Techniques & Role of lon Exchange." International Journal of Creative Research Thoughts, vol. 13, no. 11, 2025, pp. i208-i213, https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511971.
Chicago — 17th, bibliography
Ghanbahadur, Ashish Vinod, et al. "Chromatographic Techniques & Role of lon Exchange." International Journal of Creative Research Thoughts 13, no. 11 (2025): i208-i213. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511971.
Harvard — author–date
Ghanbahadur, A.V. et al. (2025) 'Chromatographic Techniques & Role of lon Exchange', International Journal of Creative Research Thoughts, 13(11), pp. i208-i213. Available at: https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511971
IEEE — numbered reference
A. V. Ghanbahadur, S. T. Daud, D. K. Vir, P. A. Waykos and V. H. Vaidya, "Chromatographic Techniques & Role of lon Exchange," IJCRT, vol. 13, no. 11, pp. i208-i213, Nov. 2025.
Vancouver — biomedical
Ghanbahadur AV, Daud ST, Vir DK, Waykos PA, Vaidya VH. Chromatographic Techniques & Role of lon Exchange. IJCRT. 2025 Nov;13(11):i208-i213.
AMA — 11th edition
Ghanbahadur AV, Daud ST, Vir DK, Waykos PA, Vaidya VH. Chromatographic Techniques & Role of lon Exchange. IJCRT. 2025;13(11):i208-i213. Accessed at https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511971
BibTeX — Zotero, Mendeley, LaTeX
@article{IJCRT2511971,
author = {Ashish Vinod Ghanbahadur and Snehal Trimbak Daud and D. K. Vir and Payal Ashok Waykos and Vaibhav Haridas Vaidya},
title = {Chromatographic Techniques & Role of lon Exchange.},
journal = {International Journal of Creative Research Thoughts},
volume = {13},
number = {11},
pages = {i208-i213},
year = {2025},
month = {November},
issn = {2320-2882},
url = {https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511971}
}
RIS — EndNote, RefWorks
TY - JOUR
AU - Ghanbahadur, Ashish Vinod
AU - Daud, Snehal Trimbak
AU - Vir, D. K.
AU - Waykos, Payal Ashok
AU - Vaidya, Vaibhav Haridas
TI - Chromatographic Techniques & Role of lon Exchange.
T2 - International Journal of Creative Research Thoughts
JA - IJCRT
VL - 13
IS - 11
PY - 2025
SN - 2320-2882
UR - https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511971
SP - i208-i213
ER -
Issue
Volume 13 Issue 11,
November-2025
Pages : i208-i213
Article Information
- Published In
- International Journal of Creative Research Thoughts — Volume 13, Issue 11, November 2025
- Pages
- i208-i213
- Published
- November 2025
- Registration ID
- IJCRT_297678
- Published Paper ID
- IJCRT2511971
- Research Area
- Pharmacy All
- Author Type
- Indian Author
- Location
- Akola, Maharashtra, India
- Peer Review
- Request Peer Review Report
- Licence
- CC BY 4.0 · Open Access
- ISSN & Impact Factor
- 2320-2882 · IF 9.17
- Downloads
- 187
- Permanent Link
- https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511971
- Published Paper PDF
- https://ijcrt.org/papers/IJCRT2511971.pdf
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