ISSN2320-2882
Impact Factor9.17
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ESTD2013
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Paper Title
Advances in Nanoglobule Formulations for the Treatment of Major Depressive Disorder
Authors
Pooja Prashant Kharosekar , Dr.Sachin R.Hangargekar , Akshay Arjun Bamankar , Harshada Balwantrao salunke , Dnyaneshwar Dagadu Dongare.
Keywords
Nanoglobules, Depression, Brain targeting, Nanotechnology, Antidepressant therapy.
Abstract
Depression is a major psychiatric disorder affecting millions globally, often associated with treatment resistance and delayed therapeutic onset. Esketamine, the S-enantiomer of ketamine, has emerged as a promising rapid-acting antidepressant targeting the NMDA receptor pathway. However, its therapeutic utility is limited by poor bioavailability, rapid metabolism, and potential systemic side effects. Nanotechnology-based drug delivery systems, particularly nanoglobules, offer a novel approach for improving the delivery of lipophilic drugs like esketamine by enhancing brain targeting and bioavailability while reducing systemic exposure. This review highlights current advances in the formulation and characterization of esketamine-loaded nanoglobules, emphasizing their potential role in improving nanotherapeutic delivery for effective management of depression.
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IJCRT — journal style
"Advances in Nanoglobule Formulations for the Treatment of Major Depressive Disorder", IJCRT - International Journal of Creative Research Thoughts (www.ijcrt.org), ISSN:2320-2882, Vol.13, Issue 11, page no.c296-c303, November 2025, Available :https://ijcrt.org/papers/IJCRT2511298.pdf
APA — 7th edition
Kharosekar, P. P., R.Hangargekar, D. S., Bamankar, A. A., salunke, H. B., & Dongare., D. D. (2025). Advances in Nanoglobule Formulations for the Treatment of Major Depressive Disorder. International Journal of Creative Research Thoughts, 13(11), c296-c303. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511298
MLA — 9th edition
Kharosekar, Pooja Prashant, et al. "Advances in Nanoglobule Formulations for the Treatment of Major Depressive Disorder." International Journal of Creative Research Thoughts, vol. 13, no. 11, 2025, pp. c296-c303, https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511298.
Chicago — 17th, bibliography
Kharosekar, Pooja Prashant, et al. "Advances in Nanoglobule Formulations for the Treatment of Major Depressive Disorder." International Journal of Creative Research Thoughts 13, no. 11 (2025): c296-c303. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511298.
Harvard — author–date
Kharosekar, P.P. et al. (2025) 'Advances in Nanoglobule Formulations for the Treatment of Major Depressive Disorder', International Journal of Creative Research Thoughts, 13(11), pp. c296-c303. Available at: https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511298
IEEE — numbered reference
P. P. Kharosekar, D. S. R.Hangargekar, A. A. Bamankar, H. B. salunke and D. D. Dongare., "Advances in Nanoglobule Formulations for the Treatment of Major Depressive Disorder," IJCRT, vol. 13, no. 11, pp. c296-c303, Nov. 2025.
Vancouver — biomedical
Kharosekar PP, R.Hangargekar DS, Bamankar AA, salunke HB, Dongare. DD. Advances in Nanoglobule Formulations for the Treatment of Major Depressive Disorder. IJCRT. 2025 Nov;13(11):c296-c303.
AMA — 11th edition
Kharosekar PP, R.Hangargekar DS, Bamankar AA, salunke HB, Dongare. DD. Advances in Nanoglobule Formulations for the Treatment of Major Depressive Disorder. IJCRT. 2025;13(11):c296-c303. Accessed at https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511298
BibTeX — Zotero, Mendeley, LaTeX
@article{IJCRT2511298,
author = {Pooja Prashant Kharosekar and Dr.Sachin R.Hangargekar and Akshay Arjun Bamankar and Harshada Balwantrao salunke and Dnyaneshwar Dagadu Dongare.},
title = {Advances in Nanoglobule Formulations for the Treatment of Major Depressive Disorder},
journal = {International Journal of Creative Research Thoughts},
volume = {13},
number = {11},
pages = {c296-c303},
year = {2025},
month = {November},
issn = {2320-2882},
url = {https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511298}
}
RIS — EndNote, RefWorks
TY - JOUR
AU - Kharosekar, Pooja Prashant
AU - R.Hangargekar, Dr.Sachin
AU - Bamankar, Akshay Arjun
AU - salunke, Harshada Balwantrao
AU - Dongare., Dnyaneshwar Dagadu
TI - Advances in Nanoglobule Formulations for the Treatment of Major Depressive Disorder
T2 - International Journal of Creative Research Thoughts
JA - IJCRT
VL - 13
IS - 11
PY - 2025
SN - 2320-2882
UR - https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511298
SP - c296-c303
ER -
Issue
Volume 13 Issue 11,
November-2025
Pages : c296-c303
Article Information
- Published In
- International Journal of Creative Research Thoughts — Volume 13, Issue 11, November 2025
- Pages
- c296-c303
- Published
- November 2025
- Registration ID
- IJCRT_296387
- Published Paper ID
- IJCRT2511298
- Research Area
- Pharmacy All
- Author Type
- Indian Author
- Location
- Latur. Dist.latur, maharashtra, India
- Peer Review
- Request Peer Review Report
- Licence
- CC BY 4.0 · Open Access
- ISSN & Impact Factor
- 2320-2882 · IF 9.17
- Downloads
- 182
- Permanent Link
- https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511298
- Published Paper PDF
- https://ijcrt.org/papers/IJCRT2511298.pdf
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International Journal of Creative Research Thoughts
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