ISSN2320-2882
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Paper Title

Oral Disintegrating Film comprehensive review

Authors

Mrunali Munindra kumbhare , Dr. Suhas Sakarkar

Keywords

Solvent casting method, Rolling Method, flexible films, Compressed film based-systems, Mucoadhesive sustained release films

Abstract

Oral dissolving films (ODFs) are advanced oral dosage forms designed for application onto the buccal mucosa, offering both local and systemic therapeutic effects. These films are often preferred over conventional oral drug delivery systems due to their flexibility, ease of use, and improved patient comfort. ODFs leverage the bioadhesive properties of certain polymers, which, upon hydration, adhere to specific mucosal regions for prolonged periods. This allows them to bypass first-pass metabolism and enhance bioavailability. Additionally, they are self-administerable, cost-effective, and exhibit high patient compliance. Among the various techniques used for formulating ODFs, the solvent casting method is the most widely employed. Typically, hydrophilic polymers are combined with other excipients to create films that disintegrate rapidly, releasing the active pharmaceutical ingredients (APIs) within seconds. ODFs provide multiple advantages, including ease of access, simple administration and withdrawal, strong mucosal retention, low enzymatic degradation, cost-efficiency, and enhanced patient compliance. These attributes contribute to their growing potential for commercial and therapeutic application. This review focuses on the mechanism of action, advantages, formulation components, preparation methods, evaluation parameters, and currently marketed ODF products. It also discusses advancements in novel fast-dissolving technologies within this drug delivery platform.

How To Cite

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IJCRT — journal style
"Oral Disintegrating Film comprehensive review", IJCRT - International Journal of Creative Research Thoughts (www.ijcrt.org), ISSN:2320-2882, Vol.13, Issue 11, page no.a19-a30, November 2025, Available :https://ijcrt.org/papers/IJCRT2511003.pdf
APA — 7th edition
kumbhare, M. M., & Sakarkar, S. (2025). Oral Disintegrating Film comprehensive review. International Journal of Creative Research Thoughts, 13(11), a19-a30. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511003
MLA — 9th edition
kumbhare, Mrunali Munindra, and Suhas Sakarkar. "Oral Disintegrating Film comprehensive review." International Journal of Creative Research Thoughts, vol. 13, no. 11, 2025, pp. a19-a30, https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511003.
Chicago — 17th, bibliography
kumbhare, Mrunali Munindra, and Suhas Sakarkar. "Oral Disintegrating Film comprehensive review." International Journal of Creative Research Thoughts 13, no. 11 (2025): a19-a30. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511003.
Harvard — author–date
kumbhare, M.M. and Sakarkar, S. (2025) 'Oral Disintegrating Film comprehensive review', International Journal of Creative Research Thoughts, 13(11), pp. a19-a30. Available at: https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511003
IEEE — numbered reference
M. M. kumbhare and S. Sakarkar, "Oral Disintegrating Film comprehensive review," IJCRT, vol. 13, no. 11, pp. a19-a30, Nov. 2025.
Vancouver — biomedical
kumbhare MM, Sakarkar S. Oral Disintegrating Film comprehensive review. IJCRT. 2025 Nov;13(11):a19-a30.
AMA — 11th edition
kumbhare MM, Sakarkar S. Oral Disintegrating Film comprehensive review. IJCRT. 2025;13(11):a19-a30. Accessed at https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511003
BibTeX — Zotero, Mendeley, LaTeX
@article{IJCRT2511003, author = {Mrunali Munindra kumbhare and Suhas Sakarkar}, title = {Oral Disintegrating Film comprehensive review}, journal = {International Journal of Creative Research Thoughts}, volume = {13}, number = {11}, pages = {a19-a30}, year = {2025}, month = {November}, issn = {2320-2882}, url = {https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511003} }
RIS — EndNote, RefWorks
TY - JOUR AU - kumbhare, Mrunali Munindra AU - Sakarkar, Suhas TI - Oral Disintegrating Film comprehensive review T2 - International Journal of Creative Research Thoughts JA - IJCRT VL - 13 IS - 11 PY - 2025 SN - 2320-2882 UR - https://ijcrt.org/viewpaperforall.php?paper=IJCRT2511003 SP - a19-a30 ER -

Issue

Volume 13 Issue 11, November-2025
Pages : a19-a30

Article Information

Pages
a19-a30
Published
November 2025
Registration ID
IJCRT_294508
Published Paper ID
IJCRT2511003
Research Area
Pharmacy All
Author Type
Indian Author
Location
bramhpuri, maharashtra, India
Licence
CC BY 4.0 · Open Access
ISSN & Impact Factor
2320-2882 · IF 9.17
Downloads
321

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International Journal of Creative Research Thoughts Published by IJCRT Publication
2320-2882 ISSN
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Licence

© 2025 — Authors hold the copyright of this article. This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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Declarations

Funding

No external funding was received for this study.

Conflict of Interest

The authors declare that they have no conflict of interest.

Acknowledgements

The authors would like to thank the reviewers and the editorial board of International Journal of Creative Research Thoughts for their careful reading and constructive comments, and all colleagues who supported the preparation of this manuscript.

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