ISSN2320-2882
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Paper Title

REVIEW ON ORAL MUCOSAL DRUG DELIVERY SYSTEM

Authors

VAISHNAVI DHORE , TEJAL NIKAM , GODAVARI KULKARNI , SUKANYA KAMANE , SHADMA SIKILKAR

Keywords

Buccal delivery, Mucoadhesive polymers, Permeation enhancers, Formulation design.

Abstract

Oral mucosal drug delivery systems have emerged as an effective alternative for delivering drugs into the body. They avoid issues like the liver breaking down drugs before they can work. This method offers better absorption and a faster effect. The oral mucosa, which has a rich supply of blood vessels, is a good surface for both local and systemic delivery. However, several challenges exist. Limited permeability, the breakdown of drugs by enzymes, and continuous saliva production can hinder how well drugs are absorbed and retained. Recent developments in mucoadhesive polymers and penetration enhancers have greatly improved the effectiveness of oral mucosal systems. These advances allow for controlled and targeted delivery of various therapeutic agents. This review discusses the physiology of the oral cavity, theories and mechanisms of mucoadhesion, factors that affect drug delivery, and the latest developments in formulation technologies aimed at enhancing therapeutic effectiveness.

How To Cite

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IJCRT — journal style
"REVIEW ON ORAL MUCOSAL DRUG DELIVERY SYSTEM", IJCRT - International Journal of Creative Research Thoughts (www.ijcrt.org), ISSN:2320-2882, Vol.13, Issue 10, page no.g844-g852, October 2025, Available :https://ijcrt.org/papers/IJCRT2510799.pdf
APA — 7th edition
DHORE, V., NIKAM, T., KULKARNI, G., KAMANE, S., & SIKILKAR, S. (2025). REVIEW ON ORAL MUCOSAL DRUG DELIVERY SYSTEM. International Journal of Creative Research Thoughts, 13(10), g844-g852. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2510799
MLA — 9th edition
DHORE, VAISHNAVI, et al. "REVIEW ON ORAL MUCOSAL DRUG DELIVERY SYSTEM." International Journal of Creative Research Thoughts, vol. 13, no. 10, 2025, pp. g844-g852, https://ijcrt.org/viewpaperforall.php?paper=IJCRT2510799.
Chicago — 17th, bibliography
DHORE, VAISHNAVI, et al. "REVIEW ON ORAL MUCOSAL DRUG DELIVERY SYSTEM." International Journal of Creative Research Thoughts 13, no. 10 (2025): g844-g852. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2510799.
Harvard — author–date
DHORE, V. et al. (2025) 'REVIEW ON ORAL MUCOSAL DRUG DELIVERY SYSTEM', International Journal of Creative Research Thoughts, 13(10), pp. g844-g852. Available at: https://ijcrt.org/viewpaperforall.php?paper=IJCRT2510799
IEEE — numbered reference
V. DHORE, T. NIKAM, G. KULKARNI, S. KAMANE and S. SIKILKAR, "REVIEW ON ORAL MUCOSAL DRUG DELIVERY SYSTEM," IJCRT, vol. 13, no. 10, pp. g844-g852, Oct. 2025.
Vancouver — biomedical
DHORE V, NIKAM T, KULKARNI G, KAMANE S, SIKILKAR S. REVIEW ON ORAL MUCOSAL DRUG DELIVERY SYSTEM. IJCRT. 2025 Oct;13(10):g844-g852.
AMA — 11th edition
DHORE V, NIKAM T, KULKARNI G, KAMANE S, SIKILKAR S. REVIEW ON ORAL MUCOSAL DRUG DELIVERY SYSTEM. IJCRT. 2025;13(10):g844-g852. Accessed at https://ijcrt.org/viewpaperforall.php?paper=IJCRT2510799
BibTeX — Zotero, Mendeley, LaTeX
@article{IJCRT2510799, author = {VAISHNAVI DHORE and TEJAL NIKAM and GODAVARI KULKARNI and SUKANYA KAMANE and SHADMA SIKILKAR}, title = {REVIEW ON ORAL MUCOSAL DRUG DELIVERY SYSTEM}, journal = {International Journal of Creative Research Thoughts}, volume = {13}, number = {10}, pages = {g844-g852}, year = {2025}, month = {October}, issn = {2320-2882}, url = {https://ijcrt.org/viewpaperforall.php?paper=IJCRT2510799} }
RIS — EndNote, RefWorks
TY - JOUR AU - DHORE, VAISHNAVI AU - NIKAM, TEJAL AU - KULKARNI, GODAVARI AU - KAMANE, SUKANYA AU - SIKILKAR, SHADMA TI - REVIEW ON ORAL MUCOSAL DRUG DELIVERY SYSTEM T2 - International Journal of Creative Research Thoughts JA - IJCRT VL - 13 IS - 10 PY - 2025 SN - 2320-2882 UR - https://ijcrt.org/viewpaperforall.php?paper=IJCRT2510799 SP - g844-g852 ER -

Issue

Volume 13 Issue 10, October-2025
Pages : g844-g852

Article Information

Pages
g844-g852
Published
October 2025
Registration ID
IJCRT_295871
Published Paper ID
IJCRT2510799
Research Area
Pharmacy All
Author Type
Indian Author
Location
Pune, Maharashtra, India
Licence
CC BY 4.0 · Open Access
ISSN & Impact Factor
2320-2882 · IF 9.17
Downloads
187

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Registration ID IJCRT_295871

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International Journal of Creative Research Thoughts Published by IJCRT Publication
2320-2882 ISSN
9.17 Impact Factor
2013 ESTD Year
Open Access
Impact Factor 9.17, calculated from Google Scholar citation data — see how it is worked out.
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Licence

© 2025 — Authors hold the copyright of this article. This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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Declarations

Funding

No external funding was received for this study.

Conflict of Interest

The authors declare that they have no conflict of interest.

Acknowledgements

The authors would like to thank the reviewers and the editorial board of International Journal of Creative Research Thoughts for their careful reading and constructive comments, and all colleagues who supported the preparation of this manuscript.

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