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Paper Title

Wrightia tinctoria And It's Therapeutic Potential A Review

Authors

TAMIL SELVI S , Dr. R. GAYATHRI , CHARAN PRAKASH K , MONIKA S

Keywords

Wrightia tinctoria, anti-psoriatic, phytochemistry, pharmacology, traditional medicine, formulation

Abstract

Objective: The present review aims to explore the therapeutic potential of Wrightia tinctoria (Roxb.) R. Br., emphasizing its traditional applications, phytochemical profile, pharmacological activities, mechanisms of action, safety aspects, and recent advancements in formulation strategies for improved clinical utility. Methodology: Relevant literature was collected from scientific databases including PubMed, Scopus, ScienceDirect, and Google Scholar, covering ethnopharmacological reports, phytochemical analyses, pharmacological investigations, and formulation studies up to 2024. Keywords used were "Wrightia tinctoria," "psoriasis," "flavonoids," "anti-inflammatory," "phytoconstituents," and "formulations." Articles focusing on traditional uses, bioactive compounds, pharmacological mechanisms, toxicity studies, and modern drug delivery systems were critically reviewed and analyzed. Results: Wrightia tinctoria was found to be traditionally employed in the treatment of dermatological, gastrointestinal, musculoskeletal, and infectious disorders. Phytochemical studies revealed the presence of flavonoids (quercetin, rutin, kaempferol), triterpenoids (lupeol, amyrin), sterols, alkaloids, glycosides, tannins, and fatty acids. Experimental evidence supports its anti-psoriatic, anti-inflammatory, antioxidant, antimicrobial, hepatoprotective, anticancer, and wound-healing activities. Mechanisms of action involve modulation of oxidative stress, inhibition of pro-inflammatory cytokines, normalization of keratinocyte proliferation, and regulation of immune pathways. Novel delivery systems such as nanoemulsions, liposomes, and phytosomes demonstrated improved bioavailability and therapeutic efficacy. Toxicological assessments indicated general safety at therapeutic doses, though comprehensive clinical validation is limited. Conclusion: Wrightia tinctoria integrates traditional knowledge with modern pharmacological evidence and represents a promising candidate for safe and effective herbal therapeutics, particularly in dermatological conditions such as psoriasis. However, large-scale clinical trials, standardization of extracts, and detailed mechanistic studies are necessary to establish its therapeutic reliability and facilitate regulatory acceptance.

How To Cite

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IJCRT — journal style
"Wrightia tinctoria And It's Therapeutic Potential A Review", IJCRT - International Journal of Creative Research Thoughts (www.ijcrt.org), ISSN:2320-2882, Vol.13, Issue 9, page no.d822-d833, September 2025, Available :https://ijcrt.org/papers/IJCRT2509446.pdf
APA — 7th edition
S, T. S., GAYATHRI, R., K, C. P., & S, M. (2025). Wrightia tinctoria And It's Therapeutic Potential A Review. International Journal of Creative Research Thoughts, 13(9), d822-d833. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2509446
MLA — 9th edition
S, TAMIL SELVI, et al. "Wrightia tinctoria And It's Therapeutic Potential A Review." International Journal of Creative Research Thoughts, vol. 13, no. 9, 2025, pp. d822-d833, https://ijcrt.org/viewpaperforall.php?paper=IJCRT2509446.
Chicago — 17th, bibliography
S, TAMIL SELVI, et al. "Wrightia tinctoria And It's Therapeutic Potential A Review." International Journal of Creative Research Thoughts 13, no. 9 (2025): d822-d833. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2509446.
Harvard — author–date
S, T.S. et al. (2025) 'Wrightia tinctoria And It's Therapeutic Potential A Review', International Journal of Creative Research Thoughts, 13(9), pp. d822-d833. Available at: https://ijcrt.org/viewpaperforall.php?paper=IJCRT2509446
IEEE — numbered reference
T. S. S, R. GAYATHRI, C. P. K and M. S, "Wrightia tinctoria And It's Therapeutic Potential A Review," IJCRT, vol. 13, no. 9, pp. d822-d833, Sep. 2025.
Vancouver — biomedical
S TS, GAYATHRI R, K CP, S M. Wrightia tinctoria And It's Therapeutic Potential A Review. IJCRT. 2025 Sep;13(9):d822-d833.
AMA — 11th edition
S TS, GAYATHRI R, K CP, S M. Wrightia tinctoria And It's Therapeutic Potential A Review. IJCRT. 2025;13(9):d822-d833. Accessed at https://ijcrt.org/viewpaperforall.php?paper=IJCRT2509446
BibTeX — Zotero, Mendeley, LaTeX
@article{IJCRT2509446, author = {TAMIL SELVI S and R. GAYATHRI and CHARAN PRAKASH K and MONIKA S}, title = {Wrightia tinctoria And It's Therapeutic Potential A Review}, journal = {International Journal of Creative Research Thoughts}, volume = {13}, number = {9}, pages = {d822-d833}, year = {2025}, month = {September}, issn = {2320-2882}, url = {https://ijcrt.org/viewpaperforall.php?paper=IJCRT2509446} }
RIS — EndNote, RefWorks
TY - JOUR AU - S, TAMIL SELVI AU - GAYATHRI, R. AU - K, CHARAN PRAKASH AU - S, MONIKA TI - Wrightia tinctoria And It's Therapeutic Potential A Review T2 - International Journal of Creative Research Thoughts JA - IJCRT VL - 13 IS - 9 PY - 2025 SN - 2320-2882 UR - https://ijcrt.org/viewpaperforall.php?paper=IJCRT2509446 SP - d822-d833 ER -

Issue

Volume 13 Issue 9, September-2025
Pages : d822-d833

Article Information

Pages
d822-d833
Published
September 2025
Registration ID
IJCRT_293993
Published Paper ID
IJCRT2509446
Research Area
Pharmacy All
Author Type
Indian Author
Location
Coimbatore, Tamil Nadu, India
Licence
CC BY 4.0 · Open Access
ISSN & Impact Factor
2320-2882 · IF 9.17
Downloads
225

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© 2025 — Authors hold the copyright of this article. This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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Declarations

Funding

No external funding was received for this study.

Conflict of Interest

The authors declare that they have no conflict of interest.

Acknowledgements

The authors would like to thank the reviewers and the editorial board of International Journal of Creative Research Thoughts for their careful reading and constructive comments, and all colleagues who supported the preparation of this manuscript.

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