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Paper Title

INTRAHEPATIC CHOLESTASIS OF PREGNANCY: MODERN INSIGHTS AND AYURVEDIC THERAPEUTIC APPROACHES"

Authors

Dr.Shireen Taj Patel , Dr.Sayali Pashte

Keywords

Keywords: ICP, Garbhini Kamala, Garbhini Paricharya

Abstract

Intrahepatic Cholestasis of Pregnancy (ICP) is a hepatobiliary disorder occurring typically in the late second and third trimesters. It is characterized by pruritus, elevated serum bile acids, and abnormal liver function tests, with potential risks such as preterm birth and fetal demise Prevalence: 0.2 - 2% of Pregnancies. It poses significant maternal discomfort and is associated with adverse perinatal outcomes such as Preterm Birth, Fetal Distress, and Sudden Intrauterine Fetal Demise. The exact etiology is Multifactorial, involving Genetic predisposition, Hormonal Influences, and Environmental factors. From an Ayurvedic standpoint, ICP closely correlates with Pittaja Vyadhi, Yakrut Vikara of Garbhini particularly involving Kamala (jaundice) and Pittaja Kandu (itching), resulting from Pitta Dushti and obstruction of Raktavaha and Pittavaha Srotas. The condition is primarily driven by Agni Mandya and Ama formation, which further exacerbate the accumulation of morbid Pitta in the Yakrita (liver). Ayurvedic management emphasizes Pitta Shamana (pacification of Pitta), Rakta Shodhana (blood purification), and Yakrit Uttejaka (liver stimulation). Dietary modifications focusing on Madhura, Sheeta, and Snigdha qualities, alongside lifestyle practices that reduce heat exposure and mental stress, are crucial to balance Pitta and ensure maternal well-being. Pre-Conceptional administration of Shodhana, Rasayana and adherence to appropriate Pathya may help in preventing the occurrence of Intrahepatic Cholestasis of Pregnancy (ICP).

How To Cite

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IJCRT — journal style
"INTRAHEPATIC CHOLESTASIS OF PREGNANCY: MODERN INSIGHTS AND AYURVEDIC THERAPEUTIC APPROACHES"", IJCRT - International Journal of Creative Research Thoughts (www.ijcrt.org), ISSN:2320-2882, Vol.13, Issue 8, page no.e528-e538, August 2025, Available :https://ijcrt.org/papers/IJCRT2508517.pdf
APA — 7th edition
Patel, D. S. T., & Pashte, D. S. (2025). INTRAHEPATIC CHOLESTASIS OF PREGNANCY: MODERN INSIGHTS AND AYURVEDIC THERAPEUTIC APPROACHES". International Journal of Creative Research Thoughts, 13(8), e528-e538. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508517
MLA — 9th edition
Patel, Dr.Shireen Taj, and Dr.Sayali Pashte. "INTRAHEPATIC CHOLESTASIS OF PREGNANCY: MODERN INSIGHTS AND AYURVEDIC THERAPEUTIC APPROACHES"." International Journal of Creative Research Thoughts, vol. 13, no. 8, 2025, pp. e528-e538, https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508517.
Chicago — 17th, bibliography
Patel, Dr.Shireen Taj, and Dr.Sayali Pashte. "INTRAHEPATIC CHOLESTASIS OF PREGNANCY: MODERN INSIGHTS AND AYURVEDIC THERAPEUTIC APPROACHES"." International Journal of Creative Research Thoughts 13, no. 8 (2025): e528-e538. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508517.
Harvard — author–date
Patel, D.S.T. and Pashte, D.S. (2025) 'INTRAHEPATIC CHOLESTASIS OF PREGNANCY: MODERN INSIGHTS AND AYURVEDIC THERAPEUTIC APPROACHES"', International Journal of Creative Research Thoughts, 13(8), pp. e528-e538. Available at: https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508517
IEEE — numbered reference
D. S. T. Patel and D. S. Pashte, "INTRAHEPATIC CHOLESTASIS OF PREGNANCY: MODERN INSIGHTS AND AYURVEDIC THERAPEUTIC APPROACHES"," IJCRT, vol. 13, no. 8, pp. e528-e538, Aug. 2025.
Vancouver — biomedical
Patel DST, Pashte DS. INTRAHEPATIC CHOLESTASIS OF PREGNANCY: MODERN INSIGHTS AND AYURVEDIC THERAPEUTIC APPROACHES". IJCRT. 2025 Aug;13(8):e528-e538.
AMA — 11th edition
Patel DST, Pashte DS. INTRAHEPATIC CHOLESTASIS OF PREGNANCY: MODERN INSIGHTS AND AYURVEDIC THERAPEUTIC APPROACHES". IJCRT. 2025;13(8):e528-e538. Accessed at https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508517
BibTeX — Zotero, Mendeley, LaTeX
@article{IJCRT2508517, author = {Dr.Shireen Taj Patel and Dr.Sayali Pashte}, title = {INTRAHEPATIC CHOLESTASIS OF PREGNANCY: MODERN INSIGHTS AND AYURVEDIC THERAPEUTIC APPROACHES"}, journal = {International Journal of Creative Research Thoughts}, volume = {13}, number = {8}, pages = {e528-e538}, year = {2025}, month = {August}, issn = {2320-2882}, url = {https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508517} }
RIS — EndNote, RefWorks
TY - JOUR AU - Patel, Dr.Shireen Taj AU - Pashte, Dr.Sayali TI - INTRAHEPATIC CHOLESTASIS OF PREGNANCY: MODERN INSIGHTS AND AYURVEDIC THERAPEUTIC APPROACHES" T2 - International Journal of Creative Research Thoughts JA - IJCRT VL - 13 IS - 8 PY - 2025 SN - 2320-2882 UR - https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508517 SP - e528-e538 ER -

Issue

Volume 13 Issue 8, August-2025
Pages : e528-e538

Article Information

Pages
e528-e538
Published
August 2025
Registration ID
IJCRT_292705
Published Paper ID
IJCRT2508517
Research Area
Health Science All
Author Type
Indian Author
Location
Ankali, Karnataka, India
Licence
CC BY 4.0 · Open Access
ISSN & Impact Factor
2320-2882 · IF 9.17
Downloads
277

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International Journal of Creative Research Thoughts Published by IJCRT Publication
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© 2025 — Authors hold the copyright of this article. This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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Declarations

Funding

No external funding was received for this study.

Conflict of Interest

The authors declare that they have no conflict of interest.

Acknowledgements

The authors would like to thank the reviewers and the editorial board of International Journal of Creative Research Thoughts for their careful reading and constructive comments, and all colleagues who supported the preparation of this manuscript.

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