ISSN2320-2882
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Paper Title

SOLID LIPID NANOPARTICLES: A NEXT-GENERATION APPROACH IN DRUG DELIVERY SYSTEMS

Authors

Anshul Choudhary , Aanchal sharma , Damandeep kaur , Davinder singh , Dr. Maninder Pal Singh

Keywords

Solid Lipid Nanoparticles (SLNs), Drug Delivery Systems, Nanotechnology, Controlled Release.

Abstract

Targeted medication delivery remains a major challenge in pharmaceutical sciences. Made of solid biodegradable lipids, Solid Lipid Nanoparticles (SLNs) are a potential colloidal carrier system that combines the advantages of polymeric nanoparticles, emulsions, and liposomes while minimizing their disadvantages. SLNs enhance bioavailability, protect labile drugs from degradation, and enable controlled, site-specific administration. This page discusses many preparation methods, including solvent-based processes, high shear homogenization, ultrasonication, microemulsion dilution, and supercritical fluid techniques. Characterization methods such particle size analysis, zeta potential measurement, electron microscopy, atomic force microscopy, and differential scanning calorimetry are highlighted. SLNs are still a developing and important technology in modern drug delivery systems, and they show versatility in a range of administration methods, including parenteral, nasal, pulmonary, ophthalmic, rectal, and topical. Despite some limitations, such as poor drug loading, sophisticated systems like Lipid Drug Conjugates (LDCs) and Nanostructured Lipid Carriers (NLCs) provide useful solutions in addition to their growing uses in gene delivery and cancer treatment.

How To Cite

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IJCRT — journal style
"SOLID LIPID NANOPARTICLES: A NEXT-GENERATION APPROACH IN DRUG DELIVERY SYSTEMS", IJCRT - International Journal of Creative Research Thoughts (www.ijcrt.org), ISSN:2320-2882, Vol.13, Issue 8, page no.e512-e519, August 2025, Available :https://ijcrt.org/papers/IJCRT2508515.pdf
APA — 7th edition
Choudhary, A., sharma, A., kaur, D., singh, D., & Singh, M. P. (2025). SOLID LIPID NANOPARTICLES: A NEXT-GENERATION APPROACH IN DRUG DELIVERY SYSTEMS. International Journal of Creative Research Thoughts, 13(8), e512-e519. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508515
MLA — 9th edition
Choudhary, Anshul, et al. "SOLID LIPID NANOPARTICLES: A NEXT-GENERATION APPROACH IN DRUG DELIVERY SYSTEMS." International Journal of Creative Research Thoughts, vol. 13, no. 8, 2025, pp. e512-e519, https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508515.
Chicago — 17th, bibliography
Choudhary, Anshul, et al. "SOLID LIPID NANOPARTICLES: A NEXT-GENERATION APPROACH IN DRUG DELIVERY SYSTEMS." International Journal of Creative Research Thoughts 13, no. 8 (2025): e512-e519. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508515.
Harvard — author–date
Choudhary, A. et al. (2025) 'SOLID LIPID NANOPARTICLES: A NEXT-GENERATION APPROACH IN DRUG DELIVERY SYSTEMS', International Journal of Creative Research Thoughts, 13(8), pp. e512-e519. Available at: https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508515
IEEE — numbered reference
A. Choudhary, A. sharma, D. kaur, D. singh and M. P. Singh, "SOLID LIPID NANOPARTICLES: A NEXT-GENERATION APPROACH IN DRUG DELIVERY SYSTEMS," IJCRT, vol. 13, no. 8, pp. e512-e519, Aug. 2025.
Vancouver — biomedical
Choudhary A, sharma A, kaur D, singh D, Singh MP. SOLID LIPID NANOPARTICLES: A NEXT-GENERATION APPROACH IN DRUG DELIVERY SYSTEMS. IJCRT. 2025 Aug;13(8):e512-e519.
AMA — 11th edition
Choudhary A, sharma A, kaur D, singh D, Singh MP. SOLID LIPID NANOPARTICLES: A NEXT-GENERATION APPROACH IN DRUG DELIVERY SYSTEMS. IJCRT. 2025;13(8):e512-e519. Accessed at https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508515
BibTeX — Zotero, Mendeley, LaTeX
@article{IJCRT2508515, author = {Anshul Choudhary and Aanchal sharma and Damandeep kaur and Davinder singh and Maninder Pal Singh}, title = {SOLID LIPID NANOPARTICLES: A NEXT-GENERATION APPROACH IN DRUG DELIVERY SYSTEMS}, journal = {International Journal of Creative Research Thoughts}, volume = {13}, number = {8}, pages = {e512-e519}, year = {2025}, month = {August}, issn = {2320-2882}, url = {https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508515} }
RIS — EndNote, RefWorks
TY - JOUR AU - Choudhary, Anshul AU - sharma, Aanchal AU - kaur, Damandeep AU - singh, Davinder AU - Singh, Maninder Pal TI - SOLID LIPID NANOPARTICLES: A NEXT-GENERATION APPROACH IN DRUG DELIVERY SYSTEMS T2 - International Journal of Creative Research Thoughts JA - IJCRT VL - 13 IS - 8 PY - 2025 SN - 2320-2882 UR - https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508515 SP - e512-e519 ER -

Issue

Volume 13 Issue 8, August-2025
Pages : e512-e519

Article Information

Pages
e512-e519
Published
August 2025
Registration ID
IJCRT_292729
Published Paper ID
IJCRT2508515
Research Area
Pharmacy All
Author Type
Indian Author
Location
KANGRA, HIMACHAL PRADESH, India
Licence
CC BY 4.0 · Open Access
ISSN & Impact Factor
2320-2882 · IF 9.17
Downloads
286

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International Journal of Creative Research Thoughts Published by IJCRT Publication
2320-2882 ISSN
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© 2025 — Authors hold the copyright of this article. This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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Declarations

Funding

No external funding was received for this study.

Conflict of Interest

The authors declare that they have no conflict of interest.

Acknowledgements

The authors would like to thank the reviewers and the editorial board of International Journal of Creative Research Thoughts for their careful reading and constructive comments, and all colleagues who supported the preparation of this manuscript.

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