ISSN2320-2882
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Paper Title

Carduus marianus (Milk Thistle) in the Treatment of Jaundice: A Comprehensive Review of Pharmacological and Clinical Evidence

Authors

Dr. Meenakshi , Dr. Shailendra Singh

Keywords

Carduus marianus ,Milk Thistle, Pharmacology ,Comprehensive ,Study

Abstract

Silybum marianum is a medicinal herb historically used as a hepatoprotective agent. It has been used for the treatment of several hepatic diseases marked by functional impairment or progressive necrosis. Its hepatoprotective function is distinctive and operates via several mechanisms, including antioxidant and "anti-inflammatory effects, regulation of cell permeability, membrane stabilisation, encouragement of liver regeneration, and suppression of collagen fibre deposition, which may contribute to cirrhosis. The majority of documented data regarding Silybum marianum pertains to hepatic disorders; however, recent findings indicate its advantageous properties across a diverse array of conditions, including renal protection, hypolipidemic and anti-atherosclerotic effects, cardiovascular protection, prevention of insulin resistance--particularly in cirrhotic patients--cancer, and Alzheimer's disease prevention. It is furthermore used as a dietary treatment. This review article intends to elucidate several facets of Silybum marianum, particularly the findings from recent publications about its impact on various disorders, in addition to discussing its hepatoprotective properties.

How To Cite

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IJCRT — journal style
"Carduus marianus (Milk Thistle) in the Treatment of Jaundice: A Comprehensive Review of Pharmacological and Clinical Evidence", IJCRT - International Journal of Creative Research Thoughts (www.ijcrt.org), ISSN:2320-2882, Vol.13, Issue 8, page no.e115-e130, August 2025, Available :https://ijcrt.org/papers/IJCRT2508470.pdf
APA — 7th edition
Meenakshi, & Singh, S. (2025). Carduus marianus (Milk Thistle) in the Treatment of Jaundice: A Comprehensive Review of Pharmacological and Clinical Evidence. International Journal of Creative Research Thoughts, 13(8), e115-e130. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508470
MLA — 9th edition
Meenakshi, and Shailendra Singh. "Carduus marianus (Milk Thistle) in the Treatment of Jaundice: A Comprehensive Review of Pharmacological and Clinical Evidence." International Journal of Creative Research Thoughts, vol. 13, no. 8, 2025, pp. e115-e130, https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508470.
Chicago — 17th, bibliography
Meenakshi, and Shailendra Singh. "Carduus marianus (Milk Thistle) in the Treatment of Jaundice: A Comprehensive Review of Pharmacological and Clinical Evidence." International Journal of Creative Research Thoughts 13, no. 8 (2025): e115-e130. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508470.
Harvard — author–date
Meenakshi and Singh, S. (2025) 'Carduus marianus (Milk Thistle) in the Treatment of Jaundice: A Comprehensive Review of Pharmacological and Clinical Evidence', International Journal of Creative Research Thoughts, 13(8), pp. e115-e130. Available at: https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508470
IEEE — numbered reference
Meenakshi and S. Singh, "Carduus marianus (Milk Thistle) in the Treatment of Jaundice: A Comprehensive Review of Pharmacological and Clinical Evidence," IJCRT, vol. 13, no. 8, pp. e115-e130, Aug. 2025.
Vancouver — biomedical
Meenakshi, Singh S. Carduus marianus (Milk Thistle) in the Treatment of Jaundice: A Comprehensive Review of Pharmacological and Clinical Evidence. IJCRT. 2025 Aug;13(8):e115-e130.
AMA — 11th edition
Meenakshi, Singh S. Carduus marianus (Milk Thistle) in the Treatment of Jaundice: A Comprehensive Review of Pharmacological and Clinical Evidence. IJCRT. 2025;13(8):e115-e130. Accessed at https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508470
BibTeX — Zotero, Mendeley, LaTeX
@article{IJCRT2508470, author = {Meenakshi and Shailendra Singh}, title = {Carduus marianus (Milk Thistle) in the Treatment of Jaundice: A Comprehensive Review of Pharmacological and Clinical Evidence}, journal = {International Journal of Creative Research Thoughts}, volume = {13}, number = {8}, pages = {e115-e130}, year = {2025}, month = {August}, issn = {2320-2882}, url = {https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508470} }
RIS — EndNote, RefWorks
TY - JOUR AU - Meenakshi AU - Singh, Shailendra TI - Carduus marianus (Milk Thistle) in the Treatment of Jaundice: A Comprehensive Review of Pharmacological and Clinical Evidence T2 - International Journal of Creative Research Thoughts JA - IJCRT VL - 13 IS - 8 PY - 2025 SN - 2320-2882 UR - https://ijcrt.org/viewpaperforall.php?paper=IJCRT2508470 SP - e115-e130 ER -

Issue

Volume 13 Issue 8, August-2025
Pages : e115-e130

Article Information

Pages
e115-e130
Published
August 2025
Registration ID
IJCRT_292673
Published Paper ID
IJCRT2508470
Research Area
Science and Technology
Author Type
Indian Author
Location
India
Licence
CC BY 4.0 · Open Access
ISSN & Impact Factor
2320-2882 · IF 9.17
Downloads
307

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About Publisher

International Journal of Creative Research Thoughts Published by IJCRT Publication
2320-2882 ISSN
9.17 Impact Factor
2013 ESTD Year
Open Access
Impact Factor 9.17, calculated from Google Scholar citation data — see how it is worked out.
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© 2025 — Authors hold the copyright of this article. This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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Declarations

Funding

No external funding was received for this study.

Conflict of Interest

The authors declare that they have no conflict of interest.

Acknowledgements

The authors would like to thank the reviewers and the editorial board of International Journal of Creative Research Thoughts for their careful reading and constructive comments, and all colleagues who supported the preparation of this manuscript.

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