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  Published Paper Details:

  Paper Title

FORMULATION AND EVALUATION OF TOPICAL DRUG DELIVERY FOR WOUND HEALING IN DIABETICS PATIENTS

  Authors

  Mrs. Anuradha U. Bhoi,  Mr. Udaykumar A. Bhoi,  Mrs. Manisha V. Mane,  Mr. Avadhut P. Jadhav,  Dr. Pravin S. Patil.

  Keywords

Vildagliptin, cream, in-vitro cell line study, Spreadability.

  Abstract


The main aim of our research was to development And Evaluation of Topical Drug Delivery for Wound Healing in Diabetic Patients. Topical route is most suitable route for skin infections. The development of topical drug delivery systems designed to have systemic effects appears to be beneficial for a number of drugs on account of the several advantages over conventional routes of drug administration. A novel cream formulation consisting of Vildagliptin was prepared. The formulation was subjected to in-vitro diffusion studies and in-vitro cell line study. No change of the physical properties was observed; the pH was in a proper range (approximately pH 4.60 to 5.78). The formulations showed good spread ability, no evidence of phase separation and good consistency during this study period. Prepared formulation show good drug release and in-vitro cell line study show the moderate wound healing activity. Batch F8 show the optimum drug release and good wound healing activity. So it is concluded that optimized batch is F8. From the present study it can be concluded that it is possible to develop creams containing Vildagliptin having wound healing property and can be used as the provision of a barrier to protect skin.

  IJCRT's Publication Details

  Unique Identification Number - IJCRT2211397

  Paper ID - 227770

  Page Number(s) - d493-d500

  Pubished in - Volume 10 | Issue 11 | November 2022

  DOI (Digital Object Identifier) -   

  Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882

  E-ISSN Number - 2320-2882

  Cite this article

  Mrs. Anuradha U. Bhoi,  Mr. Udaykumar A. Bhoi,  Mrs. Manisha V. Mane,  Mr. Avadhut P. Jadhav,  Dr. Pravin S. Patil.,   "FORMULATION AND EVALUATION OF TOPICAL DRUG DELIVERY FOR WOUND HEALING IN DIABETICS PATIENTS", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.10, Issue 11, pp.d493-d500, November 2022, Available at :http://www.ijcrt.org/papers/IJCRT2211397.pdf

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ISSN: 2320-2882
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Journal Starting Year (ESTD) : 2013
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ISSN and 7.97 Impact Factor Details


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ISSN
ISSN: 2320-2882
Impact Factor: 7.97 and ISSN APPROVED
Journal Starting Year (ESTD) : 2013
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