Published Paper Details:

Caesarean delivery is now one of the most common practices throughout the world. The most common serious side effect of spinal anaesthesia is maternal hypotension. The aim of the current study was to compare the incidence of hypotension with crystalloid pre-hydration and co-hydration in pregnant women undergoing caesarean section. This prospective study was conducted on 50 pregnant women in Parsa, Nepal. The study patients were divided into two groups (crystalloid pre-hydration group and co-hydration group) consisting of 25 patients in each group. Haemodynamic parameters such as heart rate, respiratory rate, and blood pressure were monitored. In the present study after the induction of spinal anaesthesia both systolic and diastolic blood pressure was gradually decreased from baseline among the pregnant women. the blood pressure of the pregnant women with crystalloid co-hydration was significantly higher than that of pregnant women with crystalloid pre-hydration. The occurrence of hypotension among the women with crystalloid co-hydration was significantly lower than of women with crystalloid pre-hydration. Our study shows crystalloid co-hydration administered immediately after the induction of spinal anaesthesia for caesarean section is associated with a lesser incidence of hypotension than crystalloid pre-hydration.