Published Paper Details:

Background: The plants of genus Emblica Officinalis has been used in traditional medicine for many diseases from history. Emblica Officinalis. Is also a medicinally important plant and it has been proved by modern scientific research. Objective: This study is aimed to formulate and characterize a topical gel from Emblica Officinalis leaf methanol extract and evaluate. Materials and Methods: The methanol extract was prepared by successive solvent extraction using soxhlet apparatus. Topical gel was designed to prepare by Dispersion method using Carbopol 940 as polymer. The various gel characteristics was studied by standard procedures like Homogeneity, grittiness, Extrudability, drug content, spread ability and in-vitro diffusion study. Results: The herbal gel was found homogeneous with good Extrudability, no grittiness, pH 6.79 and drug content 93.167%. The anti-inflammatory activity of herbal gel was found comparable with standard Emblica Officinalis gel and has shown 82.71% edema inhibition after 4 h of treatment. Conclusion: Emblica Officinalis gel was found suitable as a standard topical gel formulation and it can be used safely for treatment of edema.